HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,8-Diazabicyclo(5.4.0)undec-7-ene → N-[(4,6-Dimethoxypyrimidin-2-yl)aminocarbonyl]-5-formylamino-2-methoxycarbonylbenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | Carbamic acid, N-(4,6-dimethoxy-2-pyrimidinyl)-, phenyl ester | HCID 10945667 | — |
| Reactant | HCID 18924592 | HCID 18924592 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | N-[(4,6-Dimethoxypyrimidin-2-yl)aminocarbonyl]-5-formylamino-2-methoxycarbonylbenzenesulfonamide | HCID 18924588 | — |
Reaction Steps
1.00 g of 5-formylamino-2-ethoxycarbonylbenzenesulfonamide, 1.11 g of 4,6-dimethoxy-2-phenoxycarbonylaminopyrimidine and 0.82 ml of DBU in acetonitrile are reacted analogously to Chemical Example A.1; Yield: 1.00 g, M.p.: 113° to 118° C. (dec.), Mass spectrum (CI):(M+l) =454
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05747421 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-a27af7c6d8f3473b8d967435af054178 |
| Source note | uspto-grants-1998_05 |