1H-1,2,4-Triazole → HCID 17878451, compound

Participants

Reaction Steps

In substantially the same manner as in Example 2, ethyl 6-chloromethyl-4-(3,4-methylenedioxyphenyl)-2,3-dimethylthieno[2,3-b]pyridine-5-carboxylate was allowed to react with 1H-1,2,4-triazole to produce ethyl 2,3-dimethyl-4-(3,4-methylenedioxyphenyl)-6-(1,2,4-triazol-1-ylmethyl)thieno[2,3-b]pyridine-5-carboxylate. Recrystallization from ethyl acetate-hexane gave colorless prisms, m.p.109°-110° C.

Provenance & Evidence