4-Nitrobenzyl chloride → HCID 19357861, compound

HRID 1288840Notes

Reaction equation

HRID 1288840 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[CH2:16][S:15][C:14](=[O:17])[NH:13][N:12]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[N+:18]([C:21]1[CH:28]=[CH:27][C:24]([CH2:25]Cl)=[CH:23][CH:22]=1)([O-:20])=[O:19]>>[N+:18]([C:21]1[CH:28]=[CH:27][C:24]([CH2:25][N:13]2[N:12]=[C:11]([C:5]3[CH:6]=[CH:7][C:8]([O:9][CH3:10])=[C:3]([O:2][CH3:1])[CH:4]=3)[CH2:16][S:15][C:14]2=[O:17])=[CH:23][CH:22]=1)([O-:20])=[O:19]

Participants

3

Reactant 2

HCID 74824-Nitrobenzyl chlorideHCID 133658505-(3,4-Dimethoxyphenyl)-3,6-dihydro-2H-1,3,4-thiadiazin-2-one

Product 1

HCID 19357861HCID 19357861, compound

Procedure

In analogy to Example 1, the reaction of 5-(3,4-dimethoxyphenyl)-3,6-dihydro-1,3,4-thiadiazin-2-one ("B") with 4-nitrobenzyl chloride gives 3-(4-nitrobenzyl)-5-(3,4-dimethoxyphenyl)-3,6-dihydro-1,3,4-thiadiazin-2-one, m.p. 155°.

Sources & evidence

ORD record
ord-57ebc5dddb2d4f53a4ceb655b1062add
Source dataset
uspto-grants-1998_05
Patent number
US05747489

Reaction notes

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