HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 2-(Propylthio)-4,6(1H,5H)-pyrimidinedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1-Iodopropane | HCID 33643 | — |
| Reactant | HCID 178516656 | HCID 178516656 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-(Propylthio)-4,6(1H,5H)-pyrimidinedione | HCID 18924956 | — |
Reaction Steps
Propyl iodide (136 ml) was added to a suspension of 4,6-dihydroxy-2-mercaptopyrimidine (200 g) in water (800 ml), containing sodium hydroxide (55.6 g). The reaction mixture was stirred for 2 weeks then concentrated to half volume, 2N hydrochloric acid added and the product isolated by filtration (167 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05747496 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-c6629d41b7c348379951ac86c32f2734 |
| Source note | uspto-grants-1998_05 |