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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1288856Generated: November 3, 2026

4-Chloro-6,7-dimethoxyquinazoline → HCID 18924998, compound

https://huagongshe.com/reaction/1288856

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-6,7-dimethoxyquinazolineHCID 2769364—
Reactant4-Azidoaniline hydrochlorideHCID 16211210—
SolventIsopropanolHCID 3776—
ProductHCID 18924998HCID 18924998—

Reaction Steps

4-Chloro-6,7-dimethoxyquinazoline (250 mg, 1.12 mmol) and 4-azidoaniline hydrochloride (200 mg, 1.11 mmol) were refluxed in 10 mL of isopropyl alcohol for 0.5 hour, cooled and filtered to afford solid title product which was washed with 10 mL of isopropyl alcohol and dried in vacuo, at 70° C., 392 mg (98%); mp 200°-205° C. (dec).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05747498
Source datasetuspto-grants-1998_05
ORD IDord-7162b8a304cf4b7b9327ffdad566b892
Source noteuspto-grants-1998_05