HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromodecane → 4-Decyloxy-3-fluorophenyl bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromodecane | HCID 8173 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Bromo-2-fluorophenol | HCID 2724981 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | 4-Decyloxy-3-fluorophenyl bromide | HCID 14692509 | — |
Reaction Steps
A solution of 1-bromodecane in butanone was added dropwise to a stirred refluxing solution of 4-bromo-2-fluorophenol and potasium carbonate. The stirred mixture was heated under reflux for 24 hr. The potassium carbonate was filtered off and the solvent removed. The product was distilled at 130° C. at 0.05 mmHg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05750050 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-0d0eb150b336413d9098c562d198a061 |
| Source note | uspto-grants-1998_05 |