HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23206554, compound → HCID 23206537, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23206554 | HCID 23206554 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 23206537 | HCID 23206537 | 64.6% |
Reaction Steps
8.32 g of 6-trifluoromethyl-quinoline-4-phosphonic acid diethyl ester is dissolved in 100 ml of glacial acetic acid, mixed with 1.0 g of platinum dioxide and hydrogenated at room temperature. After column chromatography, 5.44 g of 6-trifluoromethyl-1,2,3,4-tetrahydroquinoline-4-phosphonic acid diethyl ester of melting point 94° C. is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05750526 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-6a368d4d311042b7aa4b3acc1d0fa9ff |
| Source note | uspto-grants-1998_05 |