Succinic anhydride → HCID 18921492, compound

Participants

Reaction Steps

Suspended in 35 ml of dichloroethane were 6.82 g (51.2 mmol) of anhydrous aluminum chloride, and 4.26 g (13.3 mmol) of 2-[(4-chlorophenyl)sulfonylaminomethyl]indane prepared in Referential Example 1 were added thereto. While chilling with ice water, 2.07 g (20.6 mmol) of succinic anhydride were added to this suspension in small portions. Thereafter, the mixture was stirred at room temperature for 1.5 hours, and the liquid reaction mixture was poured into ice water. A crystal deposited was collected by filtration, washed with water and then recrystallized from acetic acid to obtain 4.75 g of a colorless crystal. Yield: 85%.

Provenance & Evidence