Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Captamine Hydrochloride | HCID 25798 | — |
| Reactant | 5-Bromothiophene-2-carbaldehyde | HCID 78428 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 18921576 | HCID 18921576 | — |
Reaction Steps
2-dimethylaminoethanethiol hydrochloride (1.85 g, 13.09 mmol) was suspended in dry DMSO and sodium hydride (60% dispersed in mineral oil, 1.10 g, 2.1 equivs) was added carefully. The reaction mixture was left stirring for 1 hour before 5-bromo-2-thiophenecarboxaldehyde (2.5 g, 1.56 ml, 13.09 mmol) was added. The reaction mixture was then heated to 90° C. under nitrogen.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05750530 |
|---|
| Source dataset | uspto-grants-1998_05 |
|---|
| ORD ID | ord-fee46f50f23148b78597c57e1613a39e |
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| Source note | uspto-grants-1998_05 |
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