HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 18921781, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2,4-Dichloro-6-methylpyrimidine | HCID 79471 | — |
| Reactant | 1-Methyl-1,2,3,4-tetrahydroisoquinoline | HCID 92214 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18921781 | HCID 18921781 | 50.2% |
Reaction Steps
In accordance with the same procedure as in Step 1 of Example 1, except that 6-methyl-2,4-dichloropyrimidine (6.52 g, 40 mmol), 1-methyl-1,2,3,4-tetrahydroisoquinoline (6.6 g, 44 mmol), triethylamine(6.8 ml, 48.8 mmol) and N,N-dimethylformamide(30 ml) were used as starting materials, 5.5 g of the titled compound was prepared. (Yield: 50.2%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05750531 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-6eb65fa6d9c6462f83f6dc1d35b9121e |
| Source note | uspto-grants-1998_05 |