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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289499Generated: November 1, 2026

4-Fluoro-2-methylaniline → HCID 18921792, compound

https://huagongshe.com/reaction/1289499

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-2-methylanilineHCID 67982—
ReactantHCID 18921781HCID 18921781—
SolventDimethylformamideHCID 6228—
ProductHCID 18921792HCID 1892179254.7%

Reaction Steps

After 2-methyl-4-fluoroaniline(1.1 ml, 10.2 mmol) was added to a mixture solution of 6-methyl-4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-2-chloropyrimidine(1.5 g, 5.5 mmol) and dimethylformamide(10 ml), 1.2 g of the titled compound was obtained in accordance with the same procedure as in Step 2 of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750531
Source datasetuspto-grants-1998_05
ORD IDord-5f9079fdd6cf4684840b2e049cfc93dd
Source noteuspto-grants-1998_05