反应详情

After 4-fluoroaniline(1.0 ml, 10 mmol) was added to a mixture solution of 5,6-dimethyl-4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-2-chloropyrimidine(1.4 g, 4.8 mmol) and dimethylformamide(10 ml), 1.32 g of the title compound was obtained in accordance with the same procedure as in Step 2 of Example 1.