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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289523Generated: October 31, 2026

Dimethylformamide → HCID 18921704, compound

https://huagongshe.com/reaction/1289523

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
Reactant4-Fluoro-2-methylanilineHCID 67982—
ReactantHCID 18921790HCID 18921790—
ProductHCID 18921704HCID 1892170422.1%

Reaction Steps

After 4-fluoro-2-methylaniline(0.55 ml, 4.95 mmol) was added to a mixture solution of 5-methyl-6-ethyl-4-(1,2,3,4-tetrahydroisoquinolin-2-yl)-2-chloropyrimidine(0.80 g, 2.65 mmol) and dimethylformamide (5 ml), 0.25 g of the titled compound was obtained in accordance with the same procedure as in Step 2 of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750531
Source datasetuspto-grants-1998_05
ORD IDord-9acd0d6f1f5e45d4bd0bfe1472f1211f
Source noteuspto-grants-1998_05