HCID 178518333, compound → HCID 178518397, compound

Participants

Reaction Steps

A mixture solution of 2,4-dihydroxyquinazoline(39.2 g, 0.24 mol), platinium oxide(4 g) and trifluoroacetic acid(300 ml) was hydrogenated by Parr reactor for 2 hours. Platinium was filtered and the filtrate was concentrated, diluted with water, and basified with 1N-NaOH solution. The resulting solid was filtered and dried to give 13.76 g of the titled compound. (Yield: 34.5%)

Provenance & Evidence