HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-2-methylaniline → HCID 18921728, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-2-methylaniline | HCID 67982 | — |
| Reactant | HCID 18921711 | HCID 18921711 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18921728 | HCID 18921728 | 55.1% |
Reaction Steps
After 4-fluoro-2-methylaniline(0.60 ml, 5.4 mmol) was added to a mixture solution of 4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-2-chloro-5,6,7,8-tetrahydroquinazoline(0.75 g, 2.40 mmol) and dimethylformamide(5 ml), 0.58 g of the titled compound was obtained in accordance with the same procedure as in Step 2 of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05750531 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-0ea108f06c854a839d92adcc7210c535 |
| Source note | uspto-grants-1998_05 |