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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289535Generated: October 31, 2026

4-Fluoro-2-methylaniline → HCID 18921728, compound

https://huagongshe.com/reaction/1289535

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-2-methylanilineHCID 67982—
ReactantHCID 18921711HCID 18921711—
SolventDimethylformamideHCID 6228—
ProductHCID 18921728HCID 1892172855.1%

Reaction Steps

After 4-fluoro-2-methylaniline(0.60 ml, 5.4 mmol) was added to a mixture solution of 4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-2-chloro-5,6,7,8-tetrahydroquinazoline(0.75 g, 2.40 mmol) and dimethylformamide(5 ml), 0.58 g of the titled compound was obtained in accordance with the same procedure as in Step 2 of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750531
Source datasetuspto-grants-1998_05
ORD IDord-0ea108f06c854a839d92adcc7210c535
Source noteuspto-grants-1998_05