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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289554Generated: October 29, 2026

4-Fluoro-2-methylaniline → HCID 18921767, compound

https://huagongshe.com/reaction/1289554

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-2-methylanilineHCID 67982—
ReactantHCID 86752540HCID 86752540—
SolventDimethylformamideHCID 6228—
ProductHCID 18921767HCID 1892176775.6%

Reaction Steps

After 4-fluoro-2-methylaniline(0.25 ml, 2.20 mmol) was added to a mixture solution of 4-(1,2,3,4-tetrahydroisoquinolin-2-yl)-4-chlorocyclopenta[d]pyrimidine(0.58 g, 2.0 mmol) and dimethylformamide(5 ml), 0.34 g of the titled compound was obtained in accordance with the same procedure as in Step 2 of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750531
Source datasetuspto-grants-1998_05
ORD IDord-520c004ba9474f7b8435c5a5c63fa2a7
Source noteuspto-grants-1998_05