1-Methyl-1,2,3,4-tetrahydroisoquinoline → HCID 178436951, compound

Participants

Reaction Steps

In accordance with the same procedure as in Step 2 of Example 57, except that 6-ethyl-2-chloro-4-hydroxypyrimidine (7.0 g, 37.5 mmol) prepared in the above Step 1 and 1-methyl-1,2,3,4-tetrahydroisoquinoline(11.04 g, 75 mmol) were used as starting materials, 8.1 g of the titled compound was prepared. (Yield: 80%)

Provenance & Evidence