4-Fluoro-2-methylaniline → HCID 18921730, compound

Participants

Reaction Steps

After 2-methyl-4-fluoroaniline(0.42 ml, 3.8 mmol) was added to a mixture solution of 5-methyl-6-ethyl-2-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-4-chloropyrimidine(0.6 g, 2.0 mmol) and dimethylformamide(10 ml), 0.35 g of the titled compound was obtained in accordance with the same procedure as in Step 4 of Example 57.

Provenance & Evidence