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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289597Generated: November 2, 2026

4-Fluoro-2-methylaniline → HCID 18921667, compound

https://huagongshe.com/reaction/1289597

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-2-methylanilineHCID 67982—
ReactantHCID 178421594HCID 178421594—
SolventDimethylformamideHCID 6228—
ProductHCID 18921667HCID 1892166712%

Reaction Steps

After 2-methyl-4-fluoroaniline(0.46 ml, 4.2 mmol) was added to a mixture solution of 2-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-4-chlorocyclopenta[d]pyrimidine(0.6 g, 2.0 mmol) and dimethylformamide(10 ml), 0.10 g of the titled compound was obtained in accordance with the same procedure as in Step 4 of Example 57.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750531
Source datasetuspto-grants-1998_05
ORD IDord-ad9a382c1fc94a9e83a6173e3c3544ec
Source noteuspto-grants-1998_05