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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289600Generated: October 30, 2026

1,2,3,4-Tetrahydroisoquinoline → HCID 178517878, compound

https://huagongshe.com/reaction/1289600

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2,3,4-TetrahydroisoquinolineHCID 7046—
ReactantHCID 178517812HCID 178517812—
ProductHCID 178517878HCID 17851787826.3%

Reaction Steps

In accordance with the same procedure as in Step 2 of Example 57, except that 2-chloro-4-hydroxy-5,6,7,8-tetrahydroquinazoline (2.0 g, 10.8 mmol) prepared in Step 1 of Example 82 and 1,2,3,4-tetrahydroisoquinoline (2.8 g, 22.4 mmol) were used as starting materials, 0.8 g of the titled compound was prepared. (Yield: 26.3%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750531
Source datasetuspto-grants-1998_05
ORD IDord-3e896df6ba074ae6b4dad2beccc12ac2
Source noteuspto-grants-1998_05