1,2-Dichloroethane → Methyl thenoate

HRID 1289757Notes

Reaction equation

HRID 1289757 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([OH:8])=[O:7].Cl[CH2:10]CCl.S(=O)(=O)(O)O>CO>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([O:8][CH3:10])=[O:7]

Participants

5

Reactant 3

HCID 111,2-DichloroethaneHCID 1118Sulfuric AcidHCID 107002-Thiophenecarboxylic acid

Product 1

HCID 79340Methyl thenoateYield 90%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The synthesis was carried out according to the method of Example 7-(1). 2-Thiophenecarboxylic acid (25.0 g), : 1,2-dichloroethane (120 ml), methanol (23.7 ml) and concentrated sulfuric acid (0.8 ml) were used as reagents to give 24.9 g of a pale-yellow transparent liquid (yield 90%).

Sources & evidence

ORD record
ord-7d074c337b0d4d628dfc728eb7dcb299
Source dataset
uspto-grants-1998_05
Patent number
US05750545

Reaction notes

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