反应详情

The synthesis method of Example 1-(3) was applied. 3-Amino-1H-1,2,4-triazole (3.91 g), dimethylformamide (20 ml) and methyl isothiocyanate (3.41 g) were used as reagents. After the reaction, the resulting substance was removed by filtration and the filtrate was extracted with ethyl acetate, after which the obtained white solid was recrystallized from ethanol and ethyl acetate to give 1.34 g of yellow crystals (yield 18%).

1. customAfter the reaction
2. customthe resulting substance was removed by filtration
3. extractionthe filtrate was extracted with ethyl acetate
4. customafter which the obtained white solid was recrystallized from ethanol and ethyl acetate