Hydrochloric Acid → HCID 10538453, compound

Participants

Reaction Steps

The synthesis method of Example 7-(3) was applied. The compound (6.17 g) obtained in (1) above, a 0.77N aqueous sodium hydroxide solution (40 ml), methyl isothiocyanate (2.86 g) and tetrahydrofuran (40 ml) were used as reagents and the mixture was stirred at room temperature for 17 hours. 2N Hydrochloric acid (19 ml) was added to neutralize the mixture. The resulting crystals were collected by filtration and washed with hexane-ethyl acetate to give 3.55 g of white powdery crystals (yield 40%).

Provenance & Evidence