Methyl 3-(4-chlorophenyl)-2-propenoate → HCID 54445936, compound

HRID 1289787Notes

Reaction equation

HRID 1289787 reaction equation
[Cl:1][C:2]1[CH:13]=[CH:12][C:5]([CH:6]=[CH:7][C:8](OC)=O)=[CH:4][CH:3]=1.[Na].[C:15]([NH:18][NH2:19])([NH2:17])=[NH:16].Cl>CO>[NH2:17][C:15]1[N:16]=[C:8]([CH:7]=[CH:6][C:5]2[CH:12]=[CH:13][C:2]([Cl:1])=[CH:3][CH:4]=2)[NH:19][N:18]=1

Participants

5

Reactant 3

HCID 98955Methyl 3-(4-chlorophenyl)-2-propenoateHCID 5360545SodiumHCID 178418668HCID 178418668, compound

Product 1

HCID 54445936HCID 54445936, compoundYield 46%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The synthesis method of Example 7-(2) was applied. The compound (9.66 g) obtained in (1) above, methanol (140 ml), metallic sodium (5.69 g) and aminoguanidine hydrochloride (27.3 g) were used as reagents to give 4.93 g of a pale-brown solid (yield 46%).

Sources & evidence

ORD record
ord-c4b2e835e8e746b78fccba0409cd1675
Source dataset
uspto-grants-1998_05
Patent number
US05750545

Reaction notes

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