反应详情

The synthesis method of Example 1-(3) was applied. 3-Amino-1H-1,2,4-triazole (6.07 g), dimethylformamide (30 ml) and cyclohexyl isothiocyanate (20.5 ml) were used as reagents. After the reaction, the mixture was subjected to silica gel column chromatography (hexane-ethyl acetate), whereby 2.26 g of a white solid was obtained (yield 14%). The, solid was subjected to recrystallization from ethyl acetate to give colorless transparent crystals.

1. customAfter the reaction