Methyl Isocyanate → 5-Imino-N-methyl-2,5-dihydro-1H-1,2,4-triazole-1-carboximidic acid

HRID 1289795Notes

Reaction equation

HRID 1289795 reaction equation
[NH2:1][C:2]1[N:6]=[CH:5][NH:4][N:3]=1.[CH3:7][N:8]=[C:9]=[O:10]>CN(C)C=O>[NH2:1][C:2]1[N:3]([C:9]([NH:8][CH3:7])=[O:10])[N:4]=[CH:5][N:6]=1

Participants

4

Reactant 2

HCID 12228Methyl IsocyanateHCID 178418311HCID 178418311, compound

Product 1

HCID 2844685-Imino-N-methyl-2,5-dihydro-1H-1,2,4-triazole-1-carboximidic acidYield 81%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The synthesis method of Example 1-(3) was applied. 3-Amino-1H-1,2,4-triazole (5.00 g), dimethylformamide (30 ml) and methyl isocyanate (4.0 ml) were used as reagents. The mixture was stirred at room temperature i:or 18 hours and 6.83 g of the resulting solid (yield 81%) was collected by filtration. The obtained solid was recrystallized from ethyl acetate to give colorless transparent crystals.

Sources & evidence

ORD record
ord-639e28fecbd746b6b7a11c2b4627ccfc
Source dataset
uspto-grants-1998_05
Patent number
US05750545

Reaction notes

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