Methanol, 1,1-diethoxy-, 1-acetate → 2-[(Dimethylaminomethylidene)amino]-6-methyl-1,2,4-triazolo[1,5-a]-1,3,5-triazine-7(6H)-thione

HRID 1289798Notes

Reaction equation

HRID 1289798 reaction equation
[NH2:1][C:2]1[N:6]([C:7]([NH:9][CH3:10])=[S:8])[N:5]=[C:4]([N:11]=[CH:12][N:13]([CH3:15])[CH3:14])[N:3]=1.[C:16](OC(OCC)OCC)(=O)C>>[CH3:15][N:13]([CH:12]=[N:11][C:4]1[N:3]=[C:2]2[N:1]=[CH:10][N:9]([CH3:16])[C:7](=[S:8])[N:6]2[N:5]=1)[CH3:14]

Participants

3

Reactant 2

HCID 84166Methanol, 1,1-diethoxy-, 1-acetateHCID 867525445-Amino-3-[(dimethylaminomethylidene)amino]-1-[methylamino(thiocarbonyl)]-1H-1,2,4-triazole

Product 1

HCID 867525462-[(Dimethylaminomethylidene)amino]-6-methyl-1,2,4-triazolo[1,5-a]-1,3,5-triazine-7(6H)-thioneYield 56%

Procedure

The synthesis method of Example 55 was applied. The compound (486 mg) obtained in Example 33 and diethoxymethyl acetate (5 ml) were used as reagents. The mixture was reacted at 95° C. for 2 hours to give 282 mg of pale-brown crystals (yield 56%).

Workup

  1. customThe synthesis method of Example 55
  2. customThe mixture was reacted at 95° C. for 2 hours

Sources & evidence

ORD record
ord-691622487f6947b78fa0f9de9897e094
Source dataset
uspto-grants-1998_05
Patent number
US05750545

Reaction notes

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