Methanol, 1,1-diethoxy-, 1-acetate → 2-[(N-Benzylidene)amino]-6-methyl-1,2,4-triazolo[1,5-a]-1,3,5-triazine-7 (6H)-thione

HRID 1289800Notes

Reaction equation

HRID 1289800 reaction equation
[NH2:1][C:2]1[N:6]([C:7]([NH:9][CH3:10])=[S:8])[N:5]=[C:4]([N:11]=[CH:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[N:3]=1.[C:19](OC(OCC)OCC)(=O)C>>[CH:12](=[N:11][C:4]1[N:3]=[C:2]2[N:1]=[CH:10][N:9]([CH3:19])[C:7](=[S:8])[N:6]2[N:5]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 84166Methanol, 1,1-diethoxy-, 1-acetateHCID 443321545-Amino-3-[(N-benzylidene)amino]-1-[methylamino(thiocarbonyl)]-1H-1,2,4-triazole

Product 1

HCID 867525482-[(N-Benzylidene)amino]-6-methyl-1,2,4-triazolo[1,5-a]-1,3,5-triazine-7 (6H)-thioneYield 93%

Procedure

The synthesis method of Example 55 was applied. The compound (783 mg) obtained in Example 37 and diethoxymethyl acetate (5 ml) were used as reagents. The mixture was reacted at 90° C. for 1.5 hours to give 757 mg of white powdery crystals (yield 93%).

Workup

  1. customThe synthesis method of Example 55
  2. customThe mixture was reacted at 90° C. for 1.5 hours

Sources & evidence

ORD record
ord-a8810adf3fba431d9f89cfd75ccdfe35
Source dataset
uspto-grants-1998_05
Patent number
US05750545

Reaction notes

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