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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289804Generated: October 30, 2026

HCID 11132869, compound → HCID 11025076, compound

https://huagongshe.com/reaction/1289804

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 11132869HCID 11132869—
SolventHydrochloric AcidHCID 313—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 11025076HCID 11025076174.1%

Reaction Steps

1.0 g of N-(1-t-butoxycarbonylpiperidin-4-yl)-2-cyclobutyl-2-hydroxy-2-phenylacetamide was dissolved in 25 ml of a 4N hydrochloric acid solution in dioxane, and this solution was stirred at room temperature overnight. Then, the reaction mixture was evaporated to dryness under reduced pressure to obtain 0.83 g of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750540
Source datasetuspto-grants-1998_05
ORD IDord-7f263680a5fb4d00a3e1cd1391766b89
Source noteuspto-grants-1998_05