Hydrochloric Acid → [1-(4-Methyl-3-pentenyl)piperidin-4-yl] 2-cyclobutyl-2-hydroxy-2-phenylacetate

Participants

Reaction Steps

A 10% methanolic solution of hydrochloric acid was added to a solution of 2.68 g of (1-t-butoxycarbonylpiperidin-4-yl)-2-cyclobutyl-2-hydroxy-2-phenylacetate in 50 ml of methanol, and this mixture was stirred at room temperature for 10 hours. The solvent was distilled off under reduced pressure to obtain 2.24 g of the title compound.

Provenance & Evidence