5-Bromothiazole → 2-Methoxy-5-(thiazol-5-yl)benzaldehyde

Participants

Reaction Steps

The title compound was prepared by employing the method described in Example 111, Step A with (3-formyl-4-methoxyphenyl)boronic acid and the known 5-bromothiazole (E. J. Trybulski and H. J. Brabander, U.S. Pat. No. 4,990,520, 1991). NMR (400 MHz, CDCl3): δ 10.48 (s, 1H), 8.76 (s, 1H), 8.04 (s, 1H), 8.01 (d, 1H, J=2 Hz), 7.75 (dd, 1H, J=9,2 Hz), 7.05 (d, 1H, J=9 Hz), 3.97 (s, 3H). Mass spectrum (NH3 /CI): 220 (M+1).

Provenance & Evidence