2-Bromopyridine → 2-Methoxy-5-(pyridin-2-yl)benzaldehyde

HRID 1289991Notes

Reaction equation

[CH:1]([C:3]1[CH:4]=[C:5](B(O)O)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10])=[O:2].Br[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=1>>[CH3:10][O:9][C:8]1[CH:7]=[CH:6][C:5]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=2)=[CH:4][C:3]=1[CH:1]=[O:2]

Participants

Reactant 2

HCID 79732-Bromopyridine

HCID 2759225(3-Formyl-4-methoxyphenyl)boronic acid

Product 1

HCID 226200572-Methoxy-5-(pyridin-2-yl)benzaldehyde

Procedure

The title compound was prepared by employing the method described in Example 111, Step A with (3-formyl-4-methoxyphenyl)boronic acid and the commercially available 2-bromopyridine.

Sources & evidence

ORD record: ord-9e4224106ffd4b36bcb445cf392ceda4
Source dataset: uspto-grants-1998_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05750549

Reaction notes

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