Dimethyl Carbonate → HCID 18413646, compound

HRID 1290243Notes

Reaction equation

HRID 1290243 reaction equation
[C:1](=[O:6])([O:4][CH3:5])[O:2][CH3:3].[F:7][CH:8](C)[CH:9](O)CO>[OH-].[K+]>[F:7][CH:8]([CH:3]1[CH2:5][O:4][C:1](=[O:6])[O:2]1)[CH3:9]

Participants

4

Reactant 2

HCID 12021Dimethyl CarbonateHCID 13088945HCID 13088945, compound

Product 1

HCID 18413646HCID 18413646, compoundYield 136%

Reagents, catalysts & solvents 1

HCID 14797Potassium HydroxideCatalyst

Conditions

Temperature
60 °C

Procedure

2.0 g of potassium hydroxide and 50 g of dimethyl carbonate were added to 108.0 g (1.00 mol) of 3-fluoro-1,2-butanediol, and the resulting mixture was stirred at 60° C. for 12 hours. After filtering off potassium hydroxide, the mixture was distilled to obtain 101.2 g of 4-(1-fluoroethyl) -1,3-dioxolan-2-one (yield 75.5%). An elemental analysis was performed and the following values were observed:

Workup

  1. filtrationAfter filtering off potassium hydroxide
  2. distillationthe mixture was distilled

Sources & evidence

ORD record
ord-d05d0a8e8a1c4075acd5c70c484b40a5
Source dataset
uspto-grants-1998_05
Patent number
US05750730

Reaction notes

Loading…