5-Amino-2,4,6-triiodo-1,3-benzenedicarboxylic acid → 5-Amino-2,4,6-triiodoisophthaloyl dichloride

HRID 1290323Notes

Reaction equation

HRID 1290323 reaction equation
[NH2:1][C:2]1[C:3]([I:16])=[C:4]([C:13](O)=[O:14])[C:5]([I:12])=[C:6]([C:10]=1[I:11])[C:7](O)=[O:8].[Cl-:17].[Cl:18]C1N(C)CC[NH+]1C>>[NH2:1][C:2]1[C:3]([I:16])=[C:4]([C:13]([Cl:18])=[O:14])[C:5]([I:12])=[C:6]([C:10]=1[I:11])[C:7]([Cl:17])=[O:8]

Participants

3

Reactant 2

HCID 30157835-Amino-2,4,6-triiodo-1,3-benzenedicarboxylic acidHCID 109867151H-Imidazolium, 2-chloro-4,5-dihydro-1,3-dimethyl-, chloride

Product 1

HCID 98948585-Amino-2,4,6-triiodoisophthaloyl dichlorideYield 93%

Procedure

The same procedures as described in Example 7 were carried out except that the reaction of 5-amino-2,4,6-triiodoisophthalic acid and 2-chloro-1,3-dimethylimidazolinium chloride was carried out at 90°-95° C. for 6 hours. 5-Amino-2,4,6-triiodoisophthaloyl dichloride thus obtained was 5.53 g (93% yield).

Sources & evidence

ORD record
ord-fa1f98ffe32d420985bc86a50f3d66b5
Source dataset
uspto-grants-1998_05
Patent number
US05750779

Reaction notes

Loading…