Water → HCID 131719847, compound

HRID 1290384Notes

Reaction equation

HRID 1290384 reaction equation
[N+](C1C=CC(C[O:11][C:12]([C:14]2[N:15]3[CH:18]([CH:19]([CH3:36])[C:20]=2[S:21][CH:22]2[CH2:26][CH:25]([CH2:27][O:28][CH2:29][C:30]4[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=4)[O:24][CH2:23]2)[CH:17]([CH:37]([OH:39])[CH3:38])[C:16]3=[O:40])=[O:13])=CC=1)([O-])=O.C(=O)(O)[O-].[Na+:45].O>[Pd].O1CCOCC1>[Na+:45].[OH:39][CH:37]([CH:17]1[C:16](=[O:40])[N:15]2[CH:18]1[CH:19]([CH3:36])[C:20]([S:21][CH:22]1[CH2:26][CH:25]([CH2:27][O:28][CH2:29][C:30]3[CH:31]=[CH:32][CH:33]=[CH:34][CH:35]=3)[O:24][CH2:23]1)=[C:14]2[C:12]([O-:13])=[O:11])[CH3:38]

Participants

6

Reactant 3

HCID 962WaterHCID 516892Sodium BicarbonateHCID 131719849HCID 131719849, compound

Product 1

HCID 131719847HCID 131719847, compoundYield 33%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 312751,4-DioxaneSolvent

Procedure

The title compound is prepared by the procedure of Example 18 using 0.170 g of product from Example 81, 0.0277 g of sodium bicarbonate, 1.2 ml of water, 6.8 ml of dioxane, and 0.055 g of 10% palladium/carbon to give 0.045 g of desired product.

Sources & evidence

ORD record
ord-b60812f314d54697931052c2221236d5
Source dataset
uspto-grants-1998_05
Patent number
US05750735

Reaction notes

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