Water → HCID 131719852, compound

HRID 1290388Notes

Reaction equation

HRID 1290388 reaction equation
[N+](C1C=CC(C[O:11][C:12]([C:14]2[N:15]3[CH:18]([CH:19]([CH3:38])[C:20]=2[S:21][CH:22]2[CH2:26][CH:25]([CH2:27][S:28][CH:29]4[NH:34][C:33](=[O:35])[C:32](=[O:36])[NH:31][N:30]4[CH3:37])[O:24][CH2:23]2)[CH:17]([CH:39]([OH:41])[CH3:40])[C:16]3=[O:42])=[O:13])=CC=1)([O-])=O.C(=O)(O)[O-].[Na+:47].O>[Pd].O1CCOCC1>[Na+:47].[CH3:37][N:30]1[CH:29]([S:28][CH2:27][CH:25]2[O:24][CH2:23][CH:22]([S:21][C:20]3[CH:19]([CH3:38])[CH:18]4[N:15]([C:16](=[O:42])[CH:17]4[CH:39]([OH:41])[CH3:40])[C:14]=3[C:12]([O-:13])=[O:11])[CH2:26]2)[NH:34][C:33](=[O:35])[C:32](=[O:36])[NH:31]1

Participants

6

Reactant 3

HCID 962WaterHCID 516892Sodium BicarbonateHCID 131719854HCID 131719854, compound

Product 1

HCID 131719852HCID 131719852, compoundYield 46.5%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 312751,4-DioxaneSolvent

Procedure

The title compound is prepared by the procedure of Example 18 using 0.10 g of product from Example 86, 0.0135 g of sodium bicarbonate, 2 ml of water, 10 ml of dioxane, and 0.030 g of 10% palladium/carbon to give 0.038 g of the desired product.

Sources & evidence

ORD record
ord-89eb30226bea4811ab16024a5c64b635
Source dataset
uspto-grants-1998_05
Patent number
US05750735

Reaction notes

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