HCID 18916048, compound → HCID 15801175, compound

HRID 1290562Notes

Reaction equation

HRID 1290562 reaction equation
[CH3:1][C:2]1[C:11]([CH3:12])=[CH:10][CH:9]=[C:8]2[C:3]=1[N:4]=[CH:5][CH:6]=[N:7]2>C(O)C.[Ni]>[CH3:1][C:2]1[C:11]([CH3:12])=[CH:10][CH:9]=[C:8]2[C:3]=1[NH:4][CH2:5][CH2:6][NH:7]2

Participants

4

Reactant 1

HCID 18916048HCID 18916048, compound

Product 1

HCID 15801175HCID 15801175, compound

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 702EthanolSolvent

Procedure

5.3 g (0.034 mole) of 5,6-dimethylquinoxaline were dissolved in 200 ml of ethanol and, after the addition of 1 g of Raney nickel, the resulting solution was hydrogenated for 2 h at room temperature/normal pressure. After filtration, the product was concentrated to dryness and recrystallized from methyl-t-butyl ether.

Workup

  1. filtrationAfter filtration
  2. concentrationthe product was concentrated to dryness
  3. customrecrystallized from methyl-t-butyl ether

Sources & evidence

ORD record
ord-09be8a0ace6149278325e87c03570c4b
Source dataset
uspto-grants-1998_05
Patent number
US05752984

Reaction notes

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