p-Toluenesulfonic acid → HCID 21218303, compound

HRID 1290564Notes

Reaction equation

HRID 1290564 reaction equation
[CH3:1][C:2]1[C:8]([CH3:9])=[CH:7][C:6]([N+:10]([O-:12])=[O:11])=[CH:5][C:3]=1[NH2:4].[CH:13](OC)(OC)[O:14][CH3:15].C1(C)C=CC(S(O)(=O)=O)=CC=1>>[CH3:1][C:2]1[C:8]([CH3:9])=[CH:7][C:6]([N+:10]([O-:12])=[O:11])=[CH:5][C:3]=1[N:4]=[CH:13][O:14][CH3:15]

Participants

4

Reactant 3

HCID 6101p-Toluenesulfonic acidHCID 9005Trimethyl orthoformateHCID 8207862,3-Dimethyl-5-nitroaniline

Product 1

HCID 21218303HCID 21218303, compound

Procedure

66.4 g of 2,3-dimethyl-5-nitroaniline, 0.4 l of trimethyl orthoformate and 1.6 g of para-toluenesulphonic acid are mixed and heated to reflux for 3 hours.

Workup

  1. temperatureheated
  2. temperatureto reflux for 3 hours

Sources & evidence

ORD record
ord-5e5488daa31b46fc86da33cef8091652
Source dataset
uspto-grants-1998_05
Patent number
US05752982

Reaction notes

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