Potassium → HCID 21218286, compound

HRID 1290565Notes

Reaction equation

HRID 1290565 reaction equation
[K].C(OCC)(=O)C([O-])=O.[CH3:10][C:11]1[C:16]([CH3:17])=[CH:15][C:14]([N+:18]([O-:20])=[O:19])=[CH:13][C:12]=1[N:21]=[CH:22]OC>CN(C)C=O>[CH3:17][C:16]1[CH:15]=[C:14]([N+:18]([O-:20])=[O:19])[CH:13]=[C:12]2[C:11]=1[CH:10]=[CH:22][NH:21]2

Participants

5

Reactant 3

HCID 5462222PotassiumHCID 21218303HCID 21218303, compoundHCID 21943339Ethanedioic acid, monoethyl ester

Product 1

HCID 21218286HCID 21218286, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent2×

Conditions

Temperature
40 °C

Procedure

A solution of 31 g of potassium ethoxylate, 51 ml of ethyl oxalate and 0.25 l of dimethylformamide is added to a solution of methyl N-(2,3-dimethyl-5-nitrophenyl)formimidate (52 g) in 0.37 l of dimethylformamide. The temperature of the mixture is raised to 40° C. for 3 hours. The precipitate is filtered off and washed with water. The precipitate is taken up in hot isopropyl ether and then filtration is carried out.

Workup

  1. filtrationThe precipitate is filtered off
  2. washwashed with water
  3. filtrationfiltration

Sources & evidence

ORD record
ord-22a241a7c279457799d51da4b15e6f1e
Source dataset
uspto-grants-1998_05
Patent number
US05752982

Reaction notes

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