3-(1-Adamantyl)-4-methoxybenzoyl chloride → Allyl 4-[3-(1-adamantyl)-4-methoxybenzamido]benzoate

HRID 1290596Notes

Reaction equation

HRID 1290596 reaction equation
[NH2:1][C:2]1[CH:13]=[CH:12][C:5]([C:6]([O:8][CH2:9][CH:10]=[CH2:11])=[O:7])=[CH:4][CH:3]=1.[C:14]12([C:24]3[CH:25]=[C:26]([CH:30]=[CH:31][C:32]=3[O:33][CH3:34])[C:27](Cl)=[O:28])[CH2:23][CH:18]3[CH2:19][CH:20]([CH2:22][CH:16]([CH2:17]3)[CH2:15]1)[CH2:21]2>>[C:14]12([C:24]3[CH:25]=[C:26]([CH:30]=[CH:31][C:32]=3[O:33][CH3:34])[C:27]([NH:1][C:2]3[CH:3]=[CH:4][C:5]([C:6]([O:8][CH2:9][CH:10]=[CH2:11])=[O:7])=[CH:12][CH:13]=3)=[O:28])[CH2:15][CH:16]3[CH2:22][CH:20]([CH2:19][CH:18]([CH2:17]3)[CH2:23]1)[CH2:21]2

Participants

3

Reactant 2

HCID 108044973-(1-Adamantyl)-4-methoxybenzoyl chlorideHCID 13075143Prop-2-en-1-yl 4-aminobenzoate

Product 1

HCID 67590904Allyl 4-[3-(1-adamantyl)-4-methoxybenzamido]benzoate

Procedure

In a manner analogous to Example 1(a) starting with 12.6 g (71 mmoles) of allyl 4-aminobenzoate and 21.6 g (71 mmoles) of 3-(1-adamantyl)-4-methoxy benzoyl chloride, 32 g of the expected amide whose melting point is 191°-192° C. are isolated.

Workup

  1. customare isolated

Sources & evidence

ORD record
ord-0d96556a6778431daa5e51b8438ee45e
Source dataset
uspto-grants-1998_05
Patent number
US05753239

Reaction notes

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