Acetyl chloride → HCID 18916382, compound

Participants

Reaction Steps

A solution of 3.8 grams (10 mmole) of 3-(2-amino-4-chloro-6-fluorobenzoxazol-7-yl)-1-methyl-6-trifluoromethyl-2,4-(1H,3H)pyrimidinedione and 1.0 gram (15 mmole) of acetyl chloride in 20 mL of pyridine is stirred at ambient temperature for about 18 hours. The reaction mixture is concentrated under reduced pressure, yielding 3-(2-acetylamino-4-chloro-6-fluorobenzoxazol-7-yl)-1-methyl-6-trifluoromethyl-2,4-(1H,3H)pyrimidinedione.

Provenance & Evidence