N-(11-(Carbomethoxy)undecanoyl)-N-Methyl-2-Benzyloxyaniline → N-(11-(Carbomethoxy)undecanoyl)-N-Methyl-2-Hydroxy aniline

HRID 1290713Notes

Reaction equation

HRID 1290713 reaction equation
[C:1]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][C:15]([N:17]([CH3:32])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[O:24]CC1C=CC=CC=1)=[O:16])([O:3][CH3:4])=[O:2].[H][H]>CO.[Pd]>[C:1]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][C:15]([N:17]([CH3:32])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[OH:24])=[O:16])([O:3][CH3:4])=[O:2]

Participants

5

Reactant 2

HCID 18795814N-(11-(Carbomethoxy)undecanoyl)-N-Methyl-2-BenzyloxyanilineHCID 178418361HCID 178418361, compound

Product 1

HCID 54429764N-(11-(Carbomethoxy)undecanoyl)-N-Methyl-2-Hydroxy aniline

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A solution of (28) (0.11 g., 0.25 mM) in methanol (11 mL) containing 10% palladium on carbon (30 mg.) is shaken in a 40 p.s.i. hydrogen atmosphere until no (V) remained (TLC analysis). The filtered solution was then concentrated in vacuo to give the title compound (29), used immediately in step P.

Workup

  1. concentrationThe filtered solution was then concentrated in vacuo

Sources & evidence

ORD record
ord-bc99331d44024f0cae01331fc3717e18
Source dataset
uspto-grants-1998_05
Patent number
US05753641

Reaction notes

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