Benzoyl Peroxide → HCID 18919352, compound

HRID 1290818Notes

Reaction equation

HRID 1290818 reaction equation
[CH3:1][CH:2]([C:4]1[N:9]2[N:10]=[CH:11][N:12]=[C:8]2[N:7]=[CH:6][CH:5]=1)[CH3:3].[Br:13]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>ClC(Cl)(Cl)Cl>[Br:13][C:2]([C:4]1[N:9]2[N:10]=[CH:11][N:12]=[C:8]2[N:7]=[CH:6][CH:5]=1)([CH3:1])[CH3:3]

Participants

5

Reactant 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 18919358HCID 18919358, compound

Product 1

HCID 18919352HCID 18919352, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

A mixture of 7-(1-methylethyl)-1,2,4-triazolo[1,5-a]pyrimidine (4.18 g), N-bromosuccinimide (4.59 g), and dibenzoylperoxide (70 mg) in tetrachloromethane (105 ml) was stirred and heated under reflux for 11 hours. The mixture was filtered and the solvent was removed from the filtrate to give 7-(1-bromo-1-methylethyl)-1,2,4-triazolo[1,5-a]pyrimidine. Yield 2.94 g.

Workup

  1. temperatureheated
  2. temperatureunder reflux for 11 hours
  3. filtrationThe mixture was filtered
  4. customthe solvent was removed from the filtrate

Sources & evidence

ORD record
ord-1c4f9d5e78e549ba84796dfdf75a3dc4
Source dataset
uspto-grants-1998_05
Patent number
US05753665

Reaction notes

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