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Thionyl Chloride → 3-Methylbenzo[b]thiophene-2-acetyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 3-Methylbenzo[b]thiophene-2-acetic acid | HCID 2779867 | — |
| 生成物 | 3-Methylbenzo[b]thiophene-2-acetyl chloride | HCID 21837034 | — |
反応手順
A mixture of 2.0 g of 3-methylbenzo[b]thiophene-2-acetic acid and 19.4 ml of thionyl chloride is heated at reflux for 1 hour. The volatiles are evaporated in vacuo to give a residue which is concentrated from toluene three times and dried under vacuum to give 2.25 g of the desired product as a residue.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05753648 |
| 出典データセット | uspto-grants-1998_05 |
| ORD ID | ord-06a1fa68759541bebe33e831d133cd57 |
| 出典メモ | uspto-grants-1998_05 |