Thionyl Chloride → [1,1'-Biphenyl]-2-carbonyl chloride

HRID 1290927Notes

Reaction equation

HRID 1290927 reaction equation
[C:1]1([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[C:2]([C:7](O)=[O:8])=[CH:3][CH:4]=[CH:5][CH:6]=1.S(Cl)([Cl:18])=O>>[C:1]1([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[C:2]([C:7]([Cl:18])=[O:8])=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 70357o-Phenylbenzoic acid

Product 1

HCID 12563768[1,1'-Biphenyl]-2-carbonyl chloride

Procedure

A mixture of 5.6 g of 2-biphenylcarboxylic acid and 29 ml of thionyl chloride is heated on a steam bath for 0.5 hour and the volatiles removed under vacuum. Toluene (40 ml) is added (twice) and the solvent removed under vacuum to give 6.8 g of a yellow oil.

Workup

  1. temperatureis heated on a steam bath for 0.5 hour
  2. customthe volatiles removed under vacuum
  3. additionToluene (40 ml) is added (twice) and the solvent
  4. customremoved under vacuum

Sources & evidence

ORD record
ord-77025c080264465d82de5d6012beadb7
Source dataset
uspto-grants-1998_05
Patent number
US05753648

Reaction notes

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