HCID 18919750, compound → HCID 18919941, compound

Participants

Reaction Steps

0.298 g (0.000867 mol) of 1-(2-chloro-benzyl)-piperidin-4-yl 4-methyl-benzoate was dissolved in 26 ml of ether, filtered, diluted with 0.8 ml of methanol and treated with 8 ml of 1N ethereal HCI. The separated precipitate was filtered off and dried. 0.285 g (86%) of 1-(2-chloro-benzyl)-piperidin-4-yl 4-methyl-benzoate hydrochloride (1:1) was obtained as white crystals; m.p. 188°-190°.

Provenance & Evidence