HCID 18919740, compound → HCID 18919932, compound

Participants

Reaction Steps

0.182 g (0.0005 mol) of 1-(4-chloro-benzyl)-piperidin-4-yl 4-chloro-benzoate was dissolved in 15 ml of ether, filtered, diluted with 0.5 ml of methanol and treated with 5 ml of 1N ethereal HCI. The separated precipitate was filtered off and dried. 0.17 g (85%) of 1-(4-chloro-benzyl)-piperidin-4-yl 4-chloro-benzoate hydrochloride (1:1) was obtained as white crystals; m.p. 235°-237°.

Provenance & Evidence