HCID 18919757, compound → HCID 18919906, compound

Participants

Reaction Steps

0.285 g (0.00082 mol) of 1-(4-chloro-benzyl)-piperidin-4-yl 4-fluoro-benzoate was dissolved in 25 ml of ether, filtered, diluted with 8.5 ml of methanol and treated with 8.2 ml of 1N ethereal HCI. The separated precipitate was filtered off and dried. 0.277 g (88%) of 1-(4-chloro-benzyl)-piperidin-4-yl 4-fluoro-benzoate hydrochloride (1:1) was obtained as white crystals; m.p. 214°.

Provenance & Evidence