Hydrochloric Acid → HCID 18919298, compound

Participants

Reaction Steps

To a solution of 7-[4-(4-chlorobenzoyl)benzyl]-1,3-dimethylxanthine (100 mg) in methanol (4 ml) was added 4N-hydrochloric acid (1 ml) and the mixture was stirred at room temperature for 10 minutes. To this reaction mixture was added ether and the resulting precipitate was collected by filtration to provide the title compound as white powder (84 mg, 77%). 1H-NMR (CDCl3) δ: 3.45(3H,s), 3.70(3H,s), 5.70(2H,s), 7.42-7.83(8H,m), 8.47(1H,s).

Provenance & Evidence