HCID 10493689, compound → HCID 53650742, compound

Participants

Reaction Steps

In the same manner as in Reference Example 5, starting from 0.50 g of (1S)-1-[(2R)-2-(2,4-difluorophenyl)-2-oxiranyl]ethanol and 0.72 g of 1-[4-(2,2,3,3-tetrafluoropropoxy) phenyl]-2(1H, 3H)-imidazolone, 1-[(1R,2S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-methylpropyl]-3-[4-(2,2,3,3-tetrafluoropropoxy)phenyl]-2(1H,3H)-imidazolone (0.21 g) and 0.14 g of (2R)-2-(2,4-difluorophenyl)-2-[(1R)-1-[1-(4-(2,2,3,3-tetrafluoropropoxy)phenyl]-2-imidazolyloxy]ethyl]oxirane were obtained.

Provenance & Evidence